Prof. Krzysztof Sobczak

Gene Therapy Research Group


phone: +48 61 829 5766
office:   1.40A

Krzysztof finished his undergraduate studies in molecular biology at Adam Mickiewicz University in Poznan (AMU). Then, he obtained his PhD degree under the supervision of Włodzimierz Krzyżosiak (2001) and postdoctoral degree (2010), both in chemistry from the Institute of Bioorganic Chemistry PAS. He was awarded the title of professor of biology in 2019. Since 2019, he is the head of Department of Gene Expression and the director of the Institute of Molecular Biology and Biotechnology of AMU. In 2005-2009 he completed a postdoctoral fellowship at the University of Rochester (USA) in the group of Charles Thornton. In Rochester, Krzysztof started studying the molecular basis of myotonic dystrophy (DM) caused by expansion of CUG repeats in RNA, concentrating mostly on abnormalities in alternative splicing and polyadenylation. In 2010, he founded a new research group in IMBB, whose interests focus on the elucidation of the molecular pathomechanisms of human genetic diseases caused by the expansion of trinucleotide repeats, mostly DM and fragile X-associated syndromes which are caused by expansion of CGG repeats. Other aim of their study is development of therapeutic strategies targeting directly mutant RNA with antisense oligonucleotides and small compounds. His team was generously supported by the National Science Center, Foundation for Polish Science and Horizon 2020 grants. He is an author of over 70 original articles which were cited more than 4,000 times.