Our laboratory focuses on resolving the molecular details of ligand transport processes in proteins mainly relying on structural bioinformatics and computational simulations.

Our lab aims at understanding the biological importance of the 3D organization of the genome within the nucleus. We study developmental epigenetics and DNA replication.

Our lab is working on gene expression regulation in plants. Specific emphasis is given to transcriptional and posttranscriptional regulation of microRNA biogenesis and microRNA function. Model plants as well as crop plants are studied.

Our lab is working on gene expression regulation in plants. Specific emphasis is given to transcriptional and posttranscriptional regulation of microRNA biogenesis and microRNA function. Model plants as well as crop plants are studied.

The main goal of our research is to understand the mechanisms of RNA toxicity in human neurological diseases – expanded trinucleotide repeats as drivers of pathogenic protein sequestration and noncanonical translation.

We are interested in understanding the catalytic activity dependent and -independent functions of DPPIV family proteases.

Our lab’s aim is to integrate different levels of omics data information to decipher the mechanisms behind the development of pancreatic b-cells and their defects in diabetes (Polonez Bis 1 project).

We study steps of RNA processing, such as 3’end transcript maturation, posttranscriptional modifications of RNAs or further trimming of mature RNAs into smaller fragments.